The department of Nuclear Medicine was started in 1988 with two planar gamma cameras, a Headtome, a dedicated SPECT system for the head, and a dual photon X-ray bone densitometer. It was the only Nuclear Medicine department in this region at that time and offered diagnostic and therapeutic services to the people of the U.P. and neighboring states. The department performs over ten thousand diagnostic and therapeutic procedures annually using various radioisotopes at a reasonable cost.

Ever since the department has kept pace with developments in this field, continued to progress, and moved on to incorporate newer technology of SPECT-CT and acquired three such systems. After adding PET-CT imaging for general oncology and neuro-endocrine tumours, the department is counted among the leading centers of the country which offer such advanced imaging services for patients. The establishment of the Cyclotron facility in DRCL enhances the number of patients diagnosed as well as new radio-labelled tracers such as 11C-Methionine, 11C-Choline, 13N-NH3, 18F-FES, Ga-68 such as 68Ga-PSMA617, 68Ga-PSMA11, 68Ga-DOTANOC, 68Ga-FAPI04 based peptides were introduced to diagnose various diseases. With the production of Cu-64 radio-isotope, we stand first in the country, and also very few centers around the globe having such a facility. The produced Cu-64 was used for diagnostic and its therapeutic potential to be explored soon due to the capability of this isotope to be used as a therapeutic radioisotope.

 Area of Interest

  • Radiopharmaceutical Chemistry – Synthesis, radiolabeling and quality control of PET and SPECT based radiotracers.
  • Cyclotron Operations & Radioisotope Production – Production of different metals/non-metals based radioisotopes via cyclotron.
  • Bioinformatics & Molecular Docking – Analyse the potent novel scaffolds via In-Silico study through the open source / commercial software including Discovery Studio for drug discovery and molecular modelling.
  • Organic & Radiolabeling Chemistry – Designing multi-step organic synthesis, handling air-sensitive reactions, and performing radiolabeling with metal/non-metal based radioisotopes (e.g. Ga-68, Cu-64, C-11, F-18, Tc-99m, Lu-177, Zr-89 & iodine).
  • Analytical & Spectroscopic Techniques – Working on LC-MS, GC-MS, HPLC (analytical & preparative), r-TLC, well-counter, dose calibrator and proficiency in NMR, IR, and mass spectrometry (EI, ESI, FAB).
  • Automation & Instrumentation – Automated synthesizers (CFNO), metal purification systems and troubleshooting for heteroatomic organic complex molecular architectures.

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